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Posts Tagged ‘NeuroScience’

Researchers at Georgia Tech and MIT have developed a way to automate the process of finding and recording information from neurons in the living brain. The researchers have shown that a robotic arm guided by a cell-detecting computer algorithm can identify and record from neurons in the living mouse brain with better accuracy and
speed than a human experimenter. Using this technique, scientists could classify the thousands of different types of cells in the brain, map how they connect to each other, and figure out how diseased cells differ from normal cells.

Reference: S. Kodandaramaiah, G. Franzesi, B. Chow, E. Boyden, C.R. Forest, Automated whole-cell patch clamp electrophysiology of neurons in vivo. Nature Methods, Vol. 9(6), p. 585-587, May 2012. (www.nature.com/nmeth/journal/v9/n6/abs/­nmeth.1993.html)

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Researchers at Georgia Tech and the McGovern Institute for Brain Research at MIT (http://mcgovern.mit.edu/) have developed a way to automate the process of finding and recording information from neurons in the living brain. The researchers have shown that a robotic arm guided by a cell-detecting computer algorithm can identify and record from neurons in the living mouse brain with better accuracy and speed than a human experimenter. Using this technique, scientists could classify the thousands of different types of cells in the brain, map how they connect to each other, and figure out how diseased cells differ from normal cells

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In a study published on April 19, 2011 in the journal Molecular Therapy, researchers at the McGovern Institute for Brain Research at MIT and the University of Southern California used optogenetic technology to restore vision in blind mice.

Images and footage courtesy of the McGovern Institute for Brain Research at MIT, Ed Boyden, Alan Horsager, University of Southern California, Eos Neuroscience, and pond5.com

See the original video and more on MIT TechTV – http://techtv.mit.edu/videos/12312

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This animation illustrates optogenetics — a radical new technology for controlling brain activity with light.

Ed Boyden, the co-inventor of this technology, is a professor at the MIT Media Lab and at the McGovern Institute for Brain Research, where he continues to develop new technologies for controlling brain activity.

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